Insertion sequences as highly resolutive genomic markers for sequence type 1 Legionella pneumophila Paris.

ABSTRACT: The causative agent of legionellosis, Legionella pneumophila, colonizes all natural and human-made water networks, thus constituting the source of contaminated aerosols responsible for airborne human infections. Efficient control of infections, especially during epidemics, necessitates the fastest and most resolutive identification possible of the bacterial source for subsequent disinfection of reservoirs. We thus compared recognized typing approaches for Legionella with a method based on characterization of insertion sequence (IS) content. A total of 86 clinical or environmental isolates of L. pneumophila, including 84 Paris isolates, sampled from 25 clinical investigations in France between 2001 and 2007, were obtained from the Legionella National Reference Center. All strains were typed

SUBMITTER: Vergnes M 

PROVIDER: S-EPMC3020482 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature