Dynamic sex roles among men who have sex with men and transmissions from primary HIV infection.

ABSTRACT:

Background

Previous studies estimating the fraction of transmissions from persons with primary HIV have not focused on the effects of switching sex role in male homosexual populations. Such behavioral fluctuations can increase the contribution of primary HIV in the overall population.

Methods

We modeled HIV transmission with 8 compartments defined by 4 behavioral groups, with different anal-insertive and anal-receptive combinations, and 2 stages of infection. We explored the effects of fluctuating behavioral categories on endemic prevalence and the fraction of transmissions from primary HIV. We varied transition rates to develop the theory on how behavioral fluctuation affects infection patterns, and we used the transition rates in a Netherlands cohort to assess overall effe

SUBMITTER: Alam SJ 

PROVIDER: S-EPMC3021127 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature