Independent effects of age-related changes in waist circumference and BMI z scores in predicting cardiovascular disease risk factors in a prospective cohort of adolescent females.

ABSTRACT:

Background

Cross-sectional data indicate that central adiposity is associated with cardiovascular disease risk, independent of total adiposity. The use of longitudinal data to investigate the relation between changes in fat distribution and the emergence of risk factors is limited.

Objective

We tested the hypothesis that age-related change in waist circumference (to reflect central adiposity) during adolescence is a significant predictor of longitudinal change in cardiovascular disease risk, after adjustment for change in body mass index (BMI) z score (to reflect total adiposity) in a cohort of postmenarcheal adolescent females. We also tested whether race modified this relation.

Design

We analyzed publicly available data from the National Heart, Lung, and Blood Insti

SUBMITTER: Tybor DJ 

PROVIDER: S-EPMC3021431 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature