Validation of an atrial fibrillation risk algorithm in whites and African Americans.

ABSTRACT:

Background

We sought to validate a recently published risk algorithm for incident atrial fibrillation (AF) in independent cohorts and other racial groups.

Methods

We evaluated the performance of a Framingham Heart Study (FHS)-derived risk algorithm modified for 5-year incidence of AF in the FHS (n = 4764 participants) and 2 geographically and racially diverse cohorts in the age range 45 to 95 years: AGES (the Age, Gene/Environment Susceptibility-Reykjavik Study) (n = 4238) and CHS (the Cardiovascular Health Study) (n = 5410, of whom 874 [16.2%] were African Americans). The risk algorithm included age, sex, body mass index, systolic blood pressure, electrocardiographic PR interval, hypertension treatment, and heart failure.

Results

We found 1359 incident AF events in 1

SUBMITTER: Schnabel RB 

PROVIDER: S-EPMC3021784 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature