Temporal transcriptomic response during arsenic stress in Herminiimonas arsenicoxydans.

ABSTRACT:

Background

Arsenic is present in numerous ecosystems and microorganisms have developed various mechanisms to live in such hostile environments. Herminiimonas arsenicoxydans, a bacterium isolated from arsenic contaminated sludge, has acquired remarkable capabilities to cope with arsenic. In particular our previous studies have suggested the existence of a temporal induction of arsenite oxidase, a key enzyme in arsenic metabolism, in the presence of As(III).

Results

Microarrays were designed to compare gene transcription profiles under a temporal As(III) exposure. Transcriptome kinetic analysis demonstrated the existence of two phases in arsenic response. The expression of approximatively 14% of the whole genome was significantly affected by an As(III) early stress and 4% by a

SUBMITTER: Cleiss-Arnold J 

PROVIDER: S-EPMC3022917 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature