Ontology highlight
ABSTRACT:
SUBMITTER: Sun X
PROVIDER: S-EPMC3024031 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
International journal of computational biology and drug design 20091003 2
To fully understand the mechanisms governing animal development, computational models and algorithms are needed to enable quantitative studies of the underlying regulatory networks. We developed a mathematical model based on dynamic Bayesian networks to model multicellular regulatory networks that govern cell differentiation processes. A machine-learning method was developed to automatically infer such a model from heterogeneous data. We show that the model inference procedure can be greatly imp ...[more]