Ancestral and derived attributes of the dlx gene repertoire, cluster structure and expression patterns in an African cichlid fish.

ABSTRACT:

Background

Cichlid fishes have undergone rapid, expansive evolutionary radiations that are manifested in the diversification of their trophic morphologies, tooth patterning and coloration. Understanding the molecular mechanisms that underlie the cichlids' unique patterns of evolution requires a thorough examination of genes that pattern the neural crest, from which these diverse phenotypes are derived. Among those genes, the homeobox-containing Dlx gene family is of particular interest since it is involved in the patterning of the brain, jaws and teeth.

Results

In this study, we characterized the dlx genes of an African cichlid fish, Astatotilapia burtoni, to provide a baseline to later allow cross-species comparison within Cichlidae. We identified seven dlx paralogs (dlx1a,

SUBMITTER: Renz AJ 

PROVIDER: S-EPMC3024246 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature