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Genetic risk profiling for prediction of type 2 diabetes.


ABSTRACT: Type 2 diabetes (T2D) is a common disease caused by a complex interplay between many genetic and environmental factors. Candidate gene studies and recent collaborative genome-wide association efforts revealed at least 38 common single nucleotide polymorphisms (SNPs) associated with increased risk of T2D. Genetic testing of multiple SNPs is considered a potentially useful tool for early detection of individuals at high diabetes risk leading to improved targeting of preventive interventions.

SUBMITTER: Mihaescu R 

PROVIDER: S-EPMC3024707 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature