Association of tissue lineage and gene expression: conservatively and differentially expressed genes define common and special functions of tissues.

ABSTRACT:

Background

Embryogenesis is the process by which the embryo is formed, develops, and establishes developmental hierarchies of tissues. The recent advance in microarray technology made it possible to investigate the tissue specific patterns of gene expression and their relationship with tissue lineages. This study is focused on how tissue specific functions, tissue lineage, and cell differentiation are correlated, which is essential to understand embryonic development and organism complexity.

Results

We performed individual gene and gene set based analysis on multiple tissue expression data, in association with the classic topology of mammalian fate maps of embryogenesis. For each sub-group of tissues on the fate map, conservatively, differentially and correlatively expressed

SUBMITTER: Yu Y 

PROVIDER: S-EPMC3024865 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature