Comparative genomic analysis of bacteriophages specific to the channel catfish pathogen Edwardsiella ictaluri.

ABSTRACT:

Background

The bacterial pathogen Edwardsiella ictaluri is a primary cause of mortality in channel catfish raised commercially in aquaculture farms. Additional treatment and diagnostic regimes are needed for this enteric pathogen, motivating the discovery and characterization of bacteriophages specific to E. ictaluri.

Results

The genomes of three Edwardsiella ictaluri-specific bacteriophages isolated from geographically distant aquaculture ponds, at different times, were sequenced and analyzed. The genomes for phages eiAU, eiDWF, and eiMSLS are 42.80 kbp, 42.12 kbp, and 42.69 kbp, respectively, and are greater than 95% identical to each other at the nucleotide level. Nucleotide differences were mostly observed in non-coding regions and in structural proteins, with significan

SUBMITTER: Carrias A 

PROVIDER: S-EPMC3025963 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature