Intravital microscopy: a novel tool to study cell biology in living animals.

ABSTRACT: Intravital microscopy encompasses various optical microscopy techniques aimed at visualizing biological processes in live animals. In the last decade, the development of non-linear optical microscopy resulted in an enormous increase of in vivo studies, which have addressed key biological questions in fields such as neurobiology, immunology and tumor biology. Recently, few studies have shown that subcellular processes can be imaged dynamically in the live animal at a resolution comparable to that achieved in cell cultures, providing new opportunities to study cell biology under physiological conditions. The overall aim of this review is to give the reader a general idea of the potential applications of intravital microscopy with a particular emphasis on subcellular imaging. An overview of s

SUBMITTER: Weigert R 

PROVIDER: S-EPMC3027219 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature