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Spacecraft bacterium, Paenibacillus pasadenensis, causing wound infection in humans.


ABSTRACT: In a patient with mediastinitis after cardiac surgery Paenibacillus pasadenensis was detected in his sternal wound. Paenibacilli are gram-positive, aerobic, bacteria related to bacilli. Until recently these organisms were not known to cause human disease. A few cases of human infection caused by another member of this genus, P alvei, have been reported. The authors describe the first infection with P pasadenensis in humans. P pasadenensis was detected by broad-range bacterial 16S rRNA PCR. Treatment consisted of surgical debridement and antibiotics, vancomycin and ciprofloxacin followed by clindamycin and ciprofloxacin, resulting in complete recovery.

SUBMITTER: Anikpeh YF 

PROVIDER: S-EPMC3028117 | biostudies-literature | 2010

REPOSITORIES: biostudies-literature

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Spacecraft bacterium, Paenibacillus pasadenensis, causing wound infection in humans.

Anikpeh Y Flammer YF   Keller P P   Bloemberg G V GV   Grünenfelder J J   Zinkernagel A S AS  

BMJ case reports 20101229


In a patient with mediastinitis after cardiac surgery Paenibacillus pasadenensis was detected in his sternal wound. Paenibacilli are gram-positive, aerobic, bacteria related to bacilli. Until recently these organisms were not known to cause human disease. A few cases of human infection caused by another member of this genus, P alvei, have been reported. The authors describe the first infection with P pasadenensis in humans. P pasadenensis was detected by broad-range bacterial 16S rRNA PCR. Treat  ...[more]

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