Outcomes of kidney transplantation in HIV-infected recipients.

ABSTRACT:

Background

The outcomes of kidney transplantation and immunosuppression in people infected with human immunodeficiency virus (HIV) are incompletely understood.

Methods

We undertook a prospective, nonrandomized trial of kidney transplantation in HIV-infected candidates who had CD4+ T-cell counts of at least 200 per cubic millimeter and undetectable plasma HIV type 1 (HIV-1) RNA levels while being treated with a stable antiretroviral regimen. Post-transplantation management was provided in accordance with study protocols that defined prophylaxis against opportunistic infection, indications for biopsy, and acceptable approaches to immunosuppression, management of rejection, and antiretroviral therapy.

Results

Between November 2003 and June 2009, a total of 150 patients u

SUBMITTER: Stock PG 

PROVIDER: S-EPMC3028983 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature