Is apparent diffusion coefficient associated with clinical risk scores for prostate cancers that are visible on 3-T MR images?

ABSTRACT:

Purpose

To investigate whether apparent diffusion coefficients (ADCs) derived from diffusion-weighted (DW) magnetic resonance (MR) imaging at 3 T correlate with the clinical risk of prostate cancer in patients with tumors that are visible on MR images, with MR imaging/transrectal ultrasonography (US) fusion-guided biopsy as a reference.

Materials and methods

Forty-eight consecutive patients (median age, 60 years; median serum prostate-specific antigen value, 6.3 ng/mL) who underwent DW imaging during 3-T MR imaging with an endorectal coil were included in this retrospective institutional review board-approved study, and informed consent was obtained from each patient. Patients underwent targeted MR imaging/transrectal US fusion-guided prostate biopsy. Mean ADCs of cancerous

SUBMITTER: Turkbey B 

PROVIDER: S-EPMC3029887 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature