Fluorescent nucleoside analogue displays enhanced emission upon pairing with guanine.

ABSTRACT: A fluorescent nucleobase analogue, 7-aminoquinazoline-2,4-(1H,3H)-dione, is incorporated into a DNA oligonucleotide and senses mismatched pairing by displaying G-specific fluorescence enhancement.

SUBMITTER: Xie Y 

PROVIDER: S-EPMC3032630 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature