Saccharomyces cerevisiae as a model organism: a comparative study.

ABSTRACT:

Background

Model organisms are used for research because they provide a framework on which to develop and optimize methods that facilitate and standardize analysis. Such organisms should be representative of the living beings for which they are to serve as proxy. However, in practice, a model organism is often selected ad hoc, and without considering its representativeness, because a systematic and rational method to include this consideration in the selection process is still lacking.

Methodology/principal findings

In this work we propose such a method and apply it in a pilot study of strengths and limitations of Saccharomyces cerevisiae as a model organism. The method relies on the functional classification of proteins into different biological pathways and processes and o

SUBMITTER: Karathia H 

PROVIDER: S-EPMC3032731 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature