Biomarker-calibrated energy and protein consumption and cardiovascular disease risk among postmenopausal women.

ABSTRACT:

Background

Nutritional epidemiology cohort studies primarily use food frequency questionnaires (FFQs). In part because FFQs are more reliable for nutrient densities than for absolute nutrient consumption, reports from association studies typically present only nutrient density measures in relation to disease risk.

Methods

We used objective biomarkers to correct FFQ assessments for measurement error, and examined absolute energy and protein consumption in relation to cardiovascular disease incidence. FFQs and subsequent physician-adjudicated cardiovascular disease incidence were assessed for 80,370 postmenopausal women in the age range 50-79 years at enrollment in the comparison group of the Dietary Modification Trial or the prospective Observational Study in the Women's Heal

SUBMITTER: Prentice RL 

PROVIDER: S-EPMC3033986 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature