Null mutation of HvrA compensates for loss of an essential relA/spoT-like gene in Rhodobacter capsulatus.

ABSTRACT: We report that a single relA/spoT-like gene exists on the Rhodobacter capsulatus chromosome, and its mutational loss is lethal. This gene could be mutated only under a mutational background of a null mutation in the nucleoid protein HvrA. This result suggests that there may be a direct link between HvrA-regulated promoters and the ppGpp-related stringent response.

SUBMITTER: Masuda S 

PROVIDER: S-EPMC303453 | biostudies-literature | 2004 Jan

REPOSITORIES: biostudies-literature