Can rye intake decrease risk of human breast cancer?

ABSTRACT: Rye contains more fibre and bioactive compounds than other cereals used for bread production. The fibre and compounds of the fibre complex could provide protection against breast cancer (BC). To review the evidence and theoretical background for a role of rye and some of its components in the prevention of BC. A short review based to a great extent on the work by scientists in the Nordic countries. Some of the possible mechanisms by which the fibre complex could reduce BC risk are presented. The fibre through its effect on fermentation increases esterification of bile acids reducing toxicity of the free bile acids and is involved in the production of butyrate with potential anticancer effects including BC. The fibre reduces the enterohepatic circulation of the oestrogens leading to lower p

SUBMITTER: Adlercreutz H 

PROVIDER: S-EPMC3037245 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature