The components of xRNA: synthesis and fluorescence of a full genetic set of size-expanded ribonucleosides.

ABSTRACT: The synthesis and properties of a full set of four benzo-expanded ribonucleosides (xRNA), analogous to A, G, C, and U RNA monomers, are described. The nucleosides are efficient fluorophores with emission maxima of 369-411 nm. The compounds are expected to be useful as RNA pathway probes and as components of an unnatural ribopolymer.

SUBMITTER: Hernandez AR 

PROVIDER: S-EPMC3039074 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature