Hemoglobin A1c and mean glucose in patients with type 1 diabetes: analysis of data from the Juvenile Diabetes Research Foundation continuous glucose monitoring randomized trial.

ABSTRACT:

Objective

To determine the relationship between mean sensor glucose concentrations and hemoglobin A(1c) (HbA(1c)) values measured in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications laboratory at the University of Minnesota in a cohort of subjects with type 1 diabetes from the Juvenile Diabetes Research Foundation continuous glucose monitoring randomized trial.

Research design and methods

Near-continuous glucose sensor data (≥ 4 days/week) were collected for 3 months before a central laboratory-measured HbA(1c) was performed for 252 subjects aged 8-74 years, the majority of whom had stable HbA(1c) values (77% within ± 0.4% of the patient mean).

Results

The slope (95% CI) for mean sensor glucose concentration (area u

SUBMITTER: Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group 

PROVIDER: S-EPMC3041177 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature