Low-fat dietary pattern and change in body-composition traits in the Women's Health Initiative Dietary Modification Trial.

ABSTRACT:

Background

The Women's Health Initiative Dietary Modification (DM) Trial was a randomized controlled trial that compared the effects of a low-fat (≤20% of total energy) or a usual diet in relation to chronic disease risk in postmenopausal women.

Objective

We characterized long-term body-composition changes associated with the DM trial and potential modifiers of these associations.

Design

In the DM trial, 48,835 women aged 50-79 y were randomly assigned to intervention (40%) or comparison (60%) groups. We studied a subset with whole-body dual-energy X-ray absorptiometry scans at baseline and during follow-up. Changes in fat mass (FM), lean mass (LM), and percentage body fat between the intervention (n = 1580) and comparison (n = 2731) groups at years 1, 3, and 6 were c

SUBMITTER: Carty CL 

PROVIDER: S-EPMC3041598 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature