Detection of dengue-4 virus in pune, western india after an absence of 30 years--its association with two severe cases.

ABSTRACT:

Background

Difference in severity of dengue outbreaks has been related to virus serotype, genotype and clades within genotypes. Till the 1980 s, India and Sri Lanka reported low number of dengue hemorrhagic fever (DHF) cases despite circulation of all four serotypes of dengue virus (DENV). Since the 1990 s the occurrence of DHF has increased. The increase has been attributed to changes in virus lineage especially with regard to DENV-2 and DENV-3. DENV-1 has been associated with dengue fever (DF) outbreaks and DENV-4 reports have been rare. The emergence of DENV-4 was reported recently in 2003 in Delhi and in 2007 in Hyderabad. The last report of DENV-4 from Maharashtra was in 1975 from Amalner.

Results

We report on the detection of DENV-4 in Pune, Maharashtra after an absenc

SUBMITTER: Cecilia D 

PROVIDER: S-EPMC3041772 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature