Metabolic sugar signal promotes Arabidopsis meristematic proliferation via G2.

ABSTRACT: Most organs in higher plants are generated postembryonically from the meristems, which harbor continuously dividing stem cells throughout a plant's life cycle. In addition to developmental regulations, mitotic activities in the meristematic tissues are modulated by nutritional cues, including carbon source availability. Here we further analyze the relationship between the sugar signal and seedling meristem establishment, taking advantage of our previous observation that exogenously supplied metabolic sugars can rescue the meristem growth arrest phenotype of the Arabidopsis stip mutant seedlings. Our results show that metabolic sugars reactivate the stip meristems by activating the expression of key cell cycle regulators, and therefore, promoting G2 to M transition in Arabidopsis meristemat

SUBMITTER: Skylar A 

PROVIDER: S-EPMC3041830 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature