RNA-seq analyses of blood-induced changes in gene expression in the mosquito vector species, Aedes aegypti.

ABSTRACT:

Background

Hematophagy is a common trait of insect vectors of disease. Extensive genome-wide transcriptional changes occur in mosquitoes after blood meals, and these are related to digestive and reproductive processes, among others. Studies of these changes are expected to reveal molecular targets for novel vector control and pathogen transmission-blocking strategies. The mosquito Aedes aegypti (Diptera, Culicidae), a vector of Dengue viruses, Yellow Fever Virus (YFV) and Chikungunya virus (CV), is the subject of this study to look at genome-wide changes in gene expression following a blood meal.

Results

Transcriptional changes that follow a blood meal in Ae. aegypti females were explored using RNA-seq technology. Over 30% of more than 18,000 investigated transcripts accumul

SUBMITTER: Bonizzoni M 

PROVIDER: S-EPMC3042412 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature