UMARS: Un-MAppable Reads Solution.

ABSTRACT:

Background

Un-MAppable Reads Solution (UMARS) is a user-friendly web service focusing on retrieving valuable information from sequence reads that cannot be mapped back to reference genomes. Recently, next-generation sequencing (NGS) technology has emerged as a powerful tool for generating high-throughput sequencing data and has been applied to many kinds of biological research. In a typical analysis, adaptor-trimmed NGS reads were first mapped back to reference sequences, including genomes or transcripts. However, a fraction of NGS reads failed to be mapped back to the reference sequences. Such un-mappable reads are usually imputed to sequencing errors and discarded without further consideration.

Methods

We are investigating possible biological relevance and possible sources

SUBMITTER: Li SC 

PROVIDER: S-EPMC3044317 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature