Production of lantipeptides in Escherichia coli.

ABSTRACT: Lantipeptides are ribosomally synthesized and posttranslationally modified peptides containing thioether cross-links. We describe the preparation of seven different lantipeptides in Escherichia coli and demonstrate that this methodology can be used to incorporate nonproteinogenic amino acids.

SUBMITTER: Shi Y 

PROVIDER: S-EPMC3044485 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature