Stereospecific cross-coupling of secondary alkyl β-trifluoroboratoamides.

ABSTRACT: The stereospecific cross-coupling of enantioenriched nonbenzylic secondary alkyl boron compounds has been achieved. The high selectivity toward product formation over an undesired β-H elimination pathway is achieved via an intramolecular coordination of an ancillary carbonyl to the metal center in the diorganopalladium intermediate.

SUBMITTER: Sandrock DL 

PROVIDER: S-EPMC3045699 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature