Genetic, genomic, and molecular tools for studying the protoploid yeast, L. waltii.

ABSTRACT: Sequencing of the yeast Kluyveromyces waltii (recently renamed Lachancea waltii) provided evidence of a whole genome duplication event in the lineage leading to the well-studied Saccharomyces cerevisiae. While comparative genomic analyses of these yeasts have proven to be extremely instructive in modeling the loss or maintenance of gene duplicates, experimental tests of the ramifications following such genome alterations remain difficult. To transform L. waltii from an organism of the computational comparative genomic literature into an organism of the functional comparative genomic literature, we have developed genetic, molecular and genomic tools for working with L. waltii. In particular, we have characterized basic properties of L. waltii (growth, ploidy, molecular karyotype, mating typ

SUBMITTER: Di Rienzi SC 

PROVIDER: S-EPMC3046631 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature