A randomized controlled trial comparing the effects of counseling and alarm device on HAART adherence and virologic outcomes.

ABSTRACT:

Background

Behavioral interventions that promote adherence to antiretroviral medications may decrease HIV treatment failure. Antiretroviral treatment programs in sub-Saharan Africa confront increasing financial constraints to provide comprehensive HIV care, which include adherence interventions. This study compared the impact of counseling and use of an alarm device on adherence and biological outcomes in a resource-limited setting.

Methods and findings

A randomized controlled, factorial designed trial was conducted in Nairobi, Kenya. Antiretroviral-naïve individuals initiating free highly active antiretroviral therapy (HAART) in the form of fixed-dose combination pills (d4T, 3TC, and nevirapine) were randomized to one of four arms: counseling (three counseling sessions arou

SUBMITTER: Chung MH 

PROVIDER: S-EPMC3046986 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature