Dynamical modeling of the moth pheromone-sensitive olfactory receptor neuron within its sensillar environment.

ABSTRACT: In insects, olfactory receptor neurons (ORNs), surrounded with auxiliary cells and protected by a cuticular wall, form small discrete sensory organs--the sensilla. The moth pheromone-sensitive sensillum is a well studied example of hair-like sensillum that is favorable to both experimental and modeling investigations. The model presented takes into account both the molecular processes of ORNs, i.e. the biochemical reactions and ionic currents giving rise to the receptor potential, and the cellular organization and compartmentalization of the organ represented by an electrical circuit. The number of isopotential compartments needed to describe the long dendrite bearing pheromone receptors was determined. The transduction parameters that must be modified when the number of compartments is in

SUBMITTER: Gu Y 

PROVIDER: S-EPMC3047557 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature