Association of obesity with prostate cancer: a case-control study within the population-based PSA testing phase of the ProtecT study.

ABSTRACT:

Background

Obesity has been inconsistently linked to prostate cancer, mainly with mortality rather than incidence. Few large-scale studies exist assessing obesity in relation to prostate-specific antigen (PSA)-detected prostate cancer.

Methods

We used cases and stratum-matched controls from the population-based PSA-testing phase of the Prostate testing for cancer and Treatment study to examine the hypothesis that obesity as measured by body mass index (BMI), waist circumference and waist-to-hip ratio (WHR) is associated with increased prostate cancer risk, and with higher tumour stage and grade. In all, 2167 eligible cases and 11 638 randomly selected eligible controls with PSA values were recruited between 2001 and 2008. A maximum of 960 cases and 4156 controls had measurem

SUBMITTER: Dimitropoulou P 

PROVIDER: S-EPMC3048201 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature