1H, 13C, and 15N chemical shift assignments of ZCCHC9.

ABSTRACT: ZCCHC9 is a human nuclear protein with sequence homology to yeast Air1p/Air2p proteins which are RNA-binding subunits of the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex involved in nuclear RNA quality control and degradation in yeast. The ZCCHC9 protein contains four retroviral-type zinc knuckle motifs. Here, we report the NMR spectral assignment of the zinc knuckle region of ZCCHC9. These data will allow performing NMR structural and RNA-binding studies of ZCCHC9 with the aim to investigate its role in the RNA quality control in human.

SUBMITTER: Sanudo M 

PROVIDER: S-EPMC3049224 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature