2-Amino-4-(4-fluoro-phen-yl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile.

ABSTRACT: The title compound, C(22)H(14)FN(3), was prepared by a one-pot condensation using malononitrile, an aromatic aldehyde, a methyl ketone and ammonium acetate as reacta-nts under microwave irradiation. The pyridine ring is twisted with respect to the benzene ring and the naphthalene ring system, making dihedral angles of 41.9 (1) and 45.2 (1)°, respectively. In the crystal, mol-ecules are connected via inter-molecular N-H⋯N and C-H⋯F hydrogen bonds, forming a three-dimensional network.

SUBMITTER: Wang JQ 

PROVIDER: S-EPMC3050308 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature