Cardiac resynchronization therapy: a meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Studies of cardiac resynchronization therapy in addition to an implantable cardioverter defibrillator in patients with mild to moderate congestive heart failure had not been shown to reduce mortality until the recent RAFT trial (Resynchronization/Defibrillation for Ambulatory Heart Failure Trial). We performed a meta-analysis including the RAFT trial to determine the effect of cardiac resynchronization therapy with or without an implantable defibrillator on mortality.

Methods

We searched electronic databases and other sources for reports of randomized trials using a parallel or crossover design. We included studies involving patients with heart failure receiving optimal medical therapy that compared cardiac resynchronization therapy with optimal medical therapy al

SUBMITTER: Wells G 

PROVIDER: S-EPMC3050946 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature