Collateral flow predicts response to endovascular therapy for acute ischemic stroke.

ABSTRACT:

Background and purpose

Collaterals sustain the penumbra before recanalization and offset infarct growth, yet the influence of baseline collateral flow on recanalization after endovascular therapy remains relatively unexplored.

Methods

We analyzed consecutive patients who received endovascular therapy for acute cerebral ischemia from 2 distinct study populations. We assessed the relationship between pretreatment collateral grade and vascular recanalization (Thrombolysis In Myocardial Ischemia [TIMI] scale). In addition, we assessed infarct growth on serial MRI.

Results

A total of 222 patients was included, 138 from the United States and 84 from South Korea. Complete revascularization occurred in 14.1% (11 of 78) patients with poor pretreatment collateral grades, wherea

SUBMITTER: Bang OY 

PROVIDER: S-EPMC3051344 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature