5-oxo-15-HETE: total synthesis and bioactivity.

ABSTRACT: The first total synthesis of 6(E),8(Z),11(Z),13(E) 5-oxo-15-HETE 4 was accomplished. The synthetic material was evaluated with calcium mobilization assay and compared with 5-oxo-ETE the natural ligand for the OXE receptor.

SUBMITTER: Patel P 

PROVIDER: S-EPMC3052199 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature