Temporal interactions during paired-electrode stimulation in two retinal prosthesis subjects.

ABSTRACT:

Purpose

Since 2002, six blind patients have undergone implantation of an epiretinal 4 × 4 electrode array designed to directly stimulate the remaining cells of the retina after severe photoreceptor degeneration due to retinitis pigmentosa. This study was conducted to investigate how the brightness of percepts is affected by pulse timing across electrodes in two of these patients.

Methods

Subjects compared the perceived brightness of a standard stimulus (synchronous pulse trains presented across pairs of electrodes) to the perceived brightness of a test stimulus (pulse trains across the electrode pair phase shifted by 0.075, 0.375, 1.8, or 9 ms). The current amplitude necessary for each phase-shifted test stimulus to match the brightness of the standard was determined.

Res

SUBMITTER: Horsager A 

PROVIDER: S-EPMC3053297 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature