Intermittent theta-burst transcranial magnetic stimulation for treatment of Parkinson disease.

ABSTRACT:

Objective

To investigate the safety and efficacy of intermittent theta-burst stimulation (iTBS) in the treatment of motor symptoms in Parkinson disease (PD).

Background

Progression of PD is characterized by the emergence of motor deficits, which eventually respond less to dopaminergic therapy and pose a therapeutic challenge. Repetitive transcranial magnetic stimulation (rTMS) has shown promising results in improving gait, a major cause of disability, and may provide a therapeutic alternative. iTBS is a novel type of rTMS that may be more efficacious than conventional rTMS.

Methods

In this randomized, double-blind, sham-controlled study, we investigated safety and efficacy of iTBS of the motor and dorsolateral prefrontal cortices in 8 sessions over 2 weeks (evidence C

SUBMITTER: Benninger DH 

PROVIDER: S-EPMC3053339 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature