Dietary fat intake and prevention of cardiovascular disease: systematic review.

ABSTRACT:

Objective

To assess the effect of reduction or modification of dietary fat intake on total and cardiovascular mortality and cardiovascular morbidity.

Design

Systematic review.

Data sources

Cochrane Library, Medline, Embase, CAB abstracts, SIGLE, CVRCT registry, and biographies were searched; trials known to experts were included.

Included studies

Randomised controlled trials stating intention to reduce or modify fat or cholesterol intake in healthy adult participants over at least six months. Inclusion decisions, validity, and data extraction were duplicated. Meta-analysis (random effects methodology), meta-regression, and funnel plots were performed.

Results

27 studies (30 902 person years of observation) were included. Alteration of dietary fat intake

SUBMITTER: Hooper L 

PROVIDER: S-EPMC30550 | biostudies-literature | 2001 Mar

REPOSITORIES: biostudies-literature