Genomic heterogeneity within conservedmetabolic pathways of Arthrobacter species - a bioinformatic approach.

ABSTRACT: A comparative genomic analysis of three species of the soil bacterium Arthrobacter was undertaken with specific emphasis on genes involved in important and core energy metabolism pathways like glycolysis and amino acid metabolism. During the course of this study, it was revealed that codon bias of a particular species, namely Arthrobacter aurescens TC1, is significantly lower than that of the other two species A. chlorophenolicus A6 and Arthrobacter sp. FB24. The codon bias was also found to be negatively correlated with gene expression level which is determined by computing codon adaptation index of the genes. Uniformity in codon usage pattern among three species is evident in terms of genes which has high codon bias and multifunctional nature. Further, it was observed that this trend is

SUBMITTER: Pal A 

PROVIDER: S-EPMC3055160 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature