Metabolic abnormalities in children with asthma.

ABSTRACT:

Rationale

Childhood asthma and obesity have reached epidemic proportions worldwide, and the latter is also contributing to increasing rates of related metabolic disorders, such as diabetes. Yet, the relationship between asthma, obesity, and abnormal lipid and glucose metabolism is not well understood, nor has it been adequately explored in children.

Objectives

To analyze the relationship between asthma diagnosis and body mass in children across the entire range of weight percentile categories, and to test the hypothesis that early derangement in lipid and glucose metabolism is independently associated with increased risk for asthma.

Methods

Cross-sectional analysis of a representative sample of public school children from a statewide community-based screening program,

SUBMITTER: Cottrell L 

PROVIDER: S-EPMC3056222 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature