Early identification of patients at risk of acute lung injury: evaluation of lung injury prediction score in a multicenter cohort study.

ABSTRACT:

Rationale

Accurate, early identification of patients at risk for developing acute lung injury (ALI) provides the opportunity to test and implement secondary prevention strategies.

Objectives

To determine the frequency and outcome of ALI development in patients at risk and validate a lung injury prediction score (LIPS).

Methods

In this prospective multicenter observational cohort study, predisposing conditions and risk modifiers predictive of ALI development were identified from routine clinical data available during initial evaluation. The discrimination of the model was assessed with area under receiver operating curve (AUC). The risk of death from ALI was determined after adjustment for severity of illness and predisposing conditions.

Measurements and main result

SUBMITTER: Gajic O 

PROVIDER: S-EPMC3056224 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature