Systematic review highlights difficulty interpreting diverse clinical outcomes in abnormal uterine bleeding trials.

ABSTRACT:

Objectives

(1) To systematically collect and organize into clinical categories all outcomes reported in trials for abnormal uterine bleeding (AUB); (2) to rank the importance of outcomes for patient decision making; and (3) to improve future comparisons of effects in trials of AUB interventions.

Study design and setting

Systematic review of English-language randomized controlled trials of AUB treatments in MEDLINE from 1950 to June 2008. All outcomes and definitions were extracted and organized into major outcome categories by an expert group. Each outcome was ranked "critically important," "important," or "not important" for informing patients' choices.

Results

One hundred thirteen articles from 79 trials met the criteria. One hundred fourteen different outcomes were

SUBMITTER: Rahn DD 

PROVIDER: S-EPMC3057176 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature