Ontology highlight
ABSTRACT:
SUBMITTER: Simonis N
PROVIDER: S-EPMC3057923 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Nature methods 20090101 1
To provide accurate biological hypotheses and elucidate global properties of cellular networks, systematic identification of protein-protein interactions must meet high quality standards.We present an expanded C. elegans protein-protein interaction network, or 'interactome' map, derived from testing a matrix of approximately 10,000 x approximately 10,000 proteins using a highly specific, high-throughput yeast two-hybrid system. Through a new empirical quality control framework, we show that the ...[more]