Rubesanolides A and B: diterpenoids from Isodon rubescens.

ABSTRACT: From the medicinal plant Isodon rubescens, we isolated two novel diterpenes, rubesanolides A (1) and B (2). The compounds contain a unique β-lactone subgroup. This is the first discovery for a natural diterpene having rings A, B, and C in chair, boat, and twist-chair conformations, respectively. The structures were elucidated by analysis of spectroscopic data, and the absolute configuration of 1 was determined by X-ray diffraction.

SUBMITTER: Zou J 

PROVIDER: S-EPMC3057937 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature