Reported analgesic administration to rabbits undergoing experimental surgical procedures.

ABSTRACT:

Background

It has become widely accepted that whenever animals are used in scientific procedures, the 3Rs principle of replacement, reduction and refinement described by William Russell and Rex Burch should be adhered to. Animals should be replaced with non-sentient alternatives if possible, the number of animals used should be reduced and experimental procedures should be refined to minimise pain, suffering and distress. Administration of analgesic agents to animals undergoing surgical procedures is a refinement used to alleviate pain. In this study, a structured literature review was carried out to examine current trends in analgesic administration to rabbits undergoing experimental surgical procedures.

Results

128 papers from 51 peer-reviewed journals were selected for in

SUBMITTER: Coulter CA 

PROVIDER: S-EPMC3058034 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature