A topological map of the compartmentalized Arabidopsis thaliana leaf metabolome.

ABSTRACT:

Background

The extensive subcellular compartmentalization of metabolites and metabolism in eukaryotic cells is widely acknowledged and represents a key factor of metabolic activity and functionality. In striking contrast, the knowledge of actual compartmental distribution of metabolites from experimental studies is surprisingly low. However, a precise knowledge of, possibly all, metabolites and their subcellular distributions remains a key prerequisite for the understanding of any cellular function.

Methodology/principal findings

Here we describe results for the subcellular distribution of 1,117 polar and 2,804 lipophilic mass spectrometric features associated to known and unknown compounds from leaves of the model plant Arabidopsis thaliana. Using an optimized non-aqueous f

SUBMITTER: Krueger S 

PROVIDER: S-EPMC3058050 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature