Early recognition of poor prognosis in Guillain-Barre syndrome.

ABSTRACT:

Background

Guillain-Barré syndrome (GBS) has a highly diverse clinical course and outcome, yet patients are treated with a standard therapy. Patients with poor prognosis may benefit from additional treatment, provided they can be identified early, when nerve degeneration is potentially reversible and treatment is most effective. We developed a clinical prognostic model for early prediction of outcome in GBS, applicable for clinical practice and future therapeutic trials.

Methods

Data collected prospectively from a derivation cohort of 397 patients with GBS were used to identify risk factors of being unable to walk at 4 weeks, 3 months, and 6 months. Potential predictors of poor outcome (unable to walk unaided) were considered in univariable and multivariable logistic regress

SUBMITTER: Walgaard C 

PROVIDER: S-EPMC3059137 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature