Relationship between muscle sympathetic nerve activity and aortic wave reflection characteristics in young men and women.

ABSTRACT: Increased arterial stiffness is associated with higher levels of aortic wave reflection and aortic blood pressure. Recent evidence suggests a link between muscle sympathetic nerve activity and indices of arterial stiffness. Therefore, the aims of this study were to examine the relationship between resting muscle sympathetic nerve activity and characteristics of aortic pressure wave reflection and the influence of sex on these relationships. In 44 subjects (23 females and 21 males; 25 ± 1 years of age), we measured muscle sympathetic nerve activity via peroneal microneurography. In addition, noninvasive aortic pressure waveforms were synthesized from radial pressure waveforms obtained from applanation tonometry. Aortic blood pressure, augmentation index, wave reflection amplitude, and waste

SUBMITTER: Casey DP 

PROVIDER: S-EPMC3060610 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature